Core domain set

What to measure?

Outcome domains

To evaluate treatment efficacy, the first step was to determine what to measure. We have developed a core domain set (CDS) for evaluating treatment outcomes in peripheral vascular malformations (Figure below). A CDS is a minimum set of outcome domains that should be measured when evaluating treatment outcome for a certain condition. This international consensus project, including 167 physician and 134 patient/parent contributors, consisted of a three-round e-Delphi study, an online consensus meeting and a face-to-face consensus meeting.1,2

Core domain set

The figure below shows the final core domain set for peripheral vascular malformations. The full article can be found here.







Core domain set for peripheral vascular malformations. AVM = only for arteriovenous malformations, LM = only for lymphatic malformations, VM = only for venous malformations, *only relevant at follow-up.

References

1. Horbach SER, van der Horst CMAM, Blei F, van der Vleuten CJM, Frieden IJ, Richter GT, Tan ST, Muir T, Penington AJ, Boon LM, Spuls PI, OVAMA Consensus Group. Development of an international core outcome set for peripheral vascular malformations: the OVAMA project. Br J Dermatol 2018; 178: 473-81.

2. Lokhorst MM, Horbach SER, van der Horst CMAM, Spuls PI, OVAMA Steering Group. Finalizing the international core domain set for peripheral vascular malformations: the OVAMA project. Br J Dermatol 2019; 181: 1076-8.